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| Titre : | Medicinal Natural Products: A Biosynthetic Approach |
| Auteurs : | Paul Dewick |
| Type de document : | document électronique |
| Editeur : | [S.l.] : Wiley, 1997 |
| ISBN/ISSN/EAN : | 978-0-471-97478-9 |
| Index. décimale : | 615.32 (D'origine v├®g├®tale) |
| Résumé : |
Medicinal Natural Products A Biosynthetic Approach Paul M Dewick Department of Pharmaceutical Sciences, University of Nottingham, UK It has been estimated that up to 70% of the world's population is reliant on natural materials for medical treatment and in the light of the continued search for new drugs by today's pharmaceutical industry there is currently renewed interest in pharmacologically active natural products, be they from microorganisms, animals or plants. Written for undergraduate students of pharmacy, medicinal chemistry, pharmacognosy, phytochemistry, chemistry and indeed all those with an interest in natural products, Medicinal Natural Products provides a comprehensive introduction to this subject from a biosynthetic point of view. Building on fundamental chemical principles and demonstrating a unique integration of plant, microbial and animal natural products in one volume, Paul Dewick guides the reader through a wealth of diverse natural metabolites used in medicine. Sources, production methods, use as drugs and modes of action are all covered, together with semi-synthetic derivatives and synthetic analogues developed from natural product templates. Medicinal Natural Products includes extensive use of chemical schemes with annotated mechanistic explanations and is highly cross-referenced to emphasize the links and similarities among natural products. Written in a user-friendly style, this is a stimulating textbook for today's students, and an ideal starting point for project and dissertation work. ### Review "Students should be empowered for a deductive analysis of the presented substances." (*Arzneimittelforschung*, December 2009) "This new edition is an excellent text that is unrivaled in both its scope and overall coverage of natural products biosynthesis." (*Journal of Medicinal Chemistry*, August 2009) "There is no question that this is the best book available on the biosynthesis and bio-organic chemistry of medicinally important natural products." (*Education in Chemistry*, September 2009) ### From the Publisher Pharmacologically active natural products from plants, microorganisms and animals have been used for centuries in the treatment of diseases. Within the science of pharmacognosy early herbal remedies and animal extracts have been evaluated and analysed to produce both modified (semi-synthetic) extracts and synthetic analogues. This is a concise and informative textbook which provides a comprehensive introduction to natural products in medicine from a biosynthetic point of view, rather than the more usual natural product class or activity viewpoint. |
